Product Overview
Generic name: Tongxinluo capsule
Chinese Pinyin: Tongxinluo Jiaonang
Product name: Yiling
Ingredients: ginseng, leech, whole scorpion, red peony root, cicada slough, soil turtle, centipede, sandalwood, dalbergia, frankincense (prepared), wild jujube seed (fried), borneol.
Properties: This product is a hard capsule, the content is gray-brown to gray-brown granules and powder; the smell is fragrant, slightly fishy, and the taste is slightly salty and bitter.
Functions and indications: Replenishing qi and promoting blood circulation, dredging collaterals and relieving pain. Used for coronary heart disease, angina pectoris is a syndrome of deficiency of heart-qi, blood stasis and collateral obstruction. Symptoms are chest tightness, tingling, colic, immobilization, palpitations, spontaneous sweating, shortness of breath and fatigue, dark purple tongue or ecchymosis, and tight pulse Or end. It is also used for stroke of Qi deficiency, blood stasis and collateral obstruction. Symptoms are hemiplegia or numbness on the side of the body, crooked tongue and unfavorable speech.
Specification: 0.26g*30 capsules/box
Usage and dosage: Oral. 2-4 capsules at a time, 3 times a day.
Adverse reactions: Individual patients may experience stomach upset after medication.
Contraindications: hemorrhagic disorders, pregnant women and women's menstrual period and Yin deficiency and fire type strokes are contraindicated.
Note: People with stomach upset after taking the medicine should take it after meals.
Drug interactions: Drug interactions may occur if used with other drugs at the same time. Please consult your physician or pharmacist for details.
Pharmacology and Toxicology: The results of non-clinical pharmacodynamic tests suggest that this product can reduce the degree of myocardial ischemia in dogs and rats with acute myocardial infarction, reduce the scope of myocardial ischemia, improve myocardial blood supply and oxygen, and increase coronary blood flow and Left ventricular work; can reduce the myocardial no-reflow range of the porcine acute myocardial infarction reperfusion model, reduce the area of myocardial infarction; can inhibit the proliferation of myocardial collagen fibers after myocardial infarction in rats, reduce the deposition of collagen, and reduce the blood vessels in myocardial tissue The content of AngⅡ can inhibit ventricular remodeling and improve heart function; it can reduce the cerebral infarction range of the rat local cerebral ischemia model, reduce the permeability of cerebral blood vessels, and reduce cerebral edema; it can alleviate global cerebral ischemia in mice Pathological damages such as degeneration and necrosis of neuronal cells and disappearance of Nissl bodies in the model can improve neurobehavior, protect ischemic brain tissue, increase brain tissue superoxide dismutase (SOD) activity, and reduce lipid peroxidation product malondialdehyde ( MDA) content; can reduce serum total cholesterol and low-density lipoprotein in rats with hyperlipidemia, increase high-density lipoprotein, and inhibit thrombosis and platelet aggregation in rats. In addition, this product has also carried out exploratory research on the mechanism of action, and the results suggest that this product may reduce the excitatory amino acids, reduce endothelin (ET) content, inhibit endothelin gene expression, and promote Expression of vascular endothelial growth factor in rat middle cerebral artery embolism cerebral ischemia model, protect brain capillary endothelial cells, promote capillary angiogenesis; improve vascular endothelial function of rabbit atherosclerosis model, reduce endothelium-dependent vasodilation of hypercholesterolemia Function impairment, by increasing the expression of endothelial nitric oxide synthase (eNOS) gene in mice with myocardial ischemia, enhancing eNOS activity and increasing the level of nitric oxide (NO) in plasma and tissues; by inhibiting rabbit angioplasty Post-mitogen-activated protein kinase (MAPK) expression and vascular intimal proliferation, reduce blood TC, LDL-C, ET levels and increase NO levels; reduce the lipid content in the plaque of the rabbit vulnerable plaque model and increase Plaque fibrous cap thickness, lower blood lipids and plasma fibrinogen levels, inhibit the expression of inflammatory factors, and stabilize vulnerable plaques; inhibit serotonin-induced coronary artery spasm in miniature pigs; through the above multiple effects, Cardioprotective and anti-thrombosis effects.
Storage: sealed.
Packaging: Aluminum-plastic board, 30 capsules per box.
Validity period: tentatively 24 months
Approval number: National Medicine Standard Z19980015
Company Name: Shijiazhuang Yiling Pharmaceutical Co., Ltd.
Company Address: No. 238, Tianshan Street, Shijiazhuang High-tech Development Zone
