Product Overview
Generic name: capsaicin cream
Chinese Pinyin: LaJiaoJianRuGao
English name: Capsaicin Cream
Ingredients: The main ingredient of this product is capsaicin.
Properties: This product is a white cream.
Functions and indications: Suitable for relieving muscle and joint pain caused by rheumatism, as well as back pain and pain caused by sprains and strains.
Specification: 20g/piece/box
Dosage: Adults and children over 2 years old for external use. Apply evenly to the painful area, with an amount of 1-2 soybean grains each time; 3-4 times a day, children under 2 years old must follow the doctor's advice.
Adverse reactions: Occasionally, burning and tingling sensation may occur at the medication site, but it will be reduced or disappeared with time and repeated medication.
Contraindications: People who are allergic to this product and its ingredients are prohibited.
Note: 1. This product can only be used on intact skin, not on damaged skin.
2. After using this product, please wash your hands with soap and do not contact with eyes and mucous membranes.
3. This product is for external use only, do not import it.
4. Please keep it properly and keep it away from children.
5. If the local pain is not relieved after using this product for a week, please consult a physician.
Pharmacology and Toxicology: Capsaicin mainly plays an analgesic and antipruritic effect by affecting the release, synthesis and storage of neuropeptide P substance. Substance P is an undecapeptide, an important neurotransmitter, which can transmit pain and itching from peripheral nerves to spinal nerves and higher central nerves. Capsaicin mainly acts on substance P on C-type sensory neurons, and it is some non-myelinated slow-conducting fibers in C-type nerve fibers that conduct skin pain and pathological itching. Topical topical capsaicin acts on peripheral nerve axons, resulting in the reduction of substance P from all neurons (peripheral and central), thereby achieving analgesic and antipruritic effects.
Clinical research: Method of administration:
Use disposable gloves to apply 1 to 2 soybean-sized amount to the surface of the affected joint 3 times a day for 1 week.
Object:
Patients with clear joint disease.
Evaluation method:
1. Subject's evaluation of joint pain,
2. The doctor's evaluation of the subjects' joint tenderness.
3. The doctor's evaluation of the degree of joint pain in the subjects.
result:
Capsaicin Ointment with a capsaicin content of 0.025% has a total effective rate of 79.10% in the treatment of patients with clear joint pain. Although 4.48% of patients have local burning sensation to varying degrees after use, it will disappear after stopping use .
Medication for pregnant women and lactating women: This experiment has not been conducted and there is no reliable reference literature, so pregnant women and lactating women are not recommended to use this product.
Children's medication: Children must be used under the supervision of an adult.
Storage: shading, sealed, and kept in a cool place.
Packaging: Aluminum tube, 20 grams each.
Validity period: 24 months
Executive standard: WS-1023(X-763)-2002
Approval number: National Medicine Zhunzi H20030031
Company Name: Changchun Puhua Pharmaceutical Co., Ltd.
Enterprise Address: No. 1105, Huoju Road, High-tech Development Zone, Changchun City
