Product Overview
Generic name: reduced glutathione tablets
Chinese Pinyin: huanyuanxingguganpian
Product name: Atomolan
Ingredients: The main ingredient is reduced glutathione, whose chemical name is N-(N-L-γ-glutamyl-L-cysteyl)glycine.
Properties: This product is sugar-coated tablets or film-coated tablets, white after removing the sugar coating
Indications: This product is suitable for the hepatoprotective treatment of chronic hepatitis B.
Specification: 0.1g*36 pieces/box
Usage and dosage: The usual dosage for adults is 400mg (4 tablets) three times a day. The course of treatment is 12 weeks.
Adverse reactions: not yet clear
Contraindications: People who are allergic to glutathione are prohibited.
Note: 1. If rash, pale complexion, decreased blood pressure, abnormal pulse and other symptoms occur during medication, the medication should be stopped immediately.
2. Use the dissolved solution immediately, and the remaining liquid can not be used again.
3. Intramuscular injection should only be used when this route is needed, and repeated injections at the same site should be avoided.
Drug interactions: This product should not be mixed with vitamin B12, vitamin K3, menadione, calcium pantothenate, orotic acid, antihistamines, sulfa drugs and tetracycline.
Pharmacology and Toxicology: Reduced glutathione is a tripeptide compound containing sulfhydryl (SH), which has important physiological activities such as activating the redox system, activating SH enzyme, and detoxification in the human body. Reduced glutathione participates in the tricarboxylic acid cycle and sugar metabolism in the body, promotes the production of high energy in the body, and acts as a coenzyme. Reduced glutathione is the prosthetic group of glyceraldehyde phosphate dehydrogenase and the coenzyme of glyoxalase and triose phosphate dehydrogenase. Reduced glutathione can activate SH enzymes in the body, promote the metabolism of carbohydrates, fats and proteins to regulate the metabolic process of cell membranes. Reduced glutathione participates in the combination of a variety of exogenous and endogenous toxic substances to produce attenuated substances.
Pharmacokinetics: According to the literature, 10 healthy male volunteers took 600mg glutathione tablets (foreign products) orally in a single dose, and the peak time of blood glutathione concentration was 1.35±; 0.20h, glutathione The peak concentration (Cmax) is 23.79±; 7.15μ mol/L, and the area under the drug-time curve (AUC) is 74.49±; 16.49μ mol/(L· ;h).
Storage: sealed.
Packaging: Aluminum-plastic packaging, 36 pieces per box.
Validity period: 24 months
Executive standard: Standard of the State Food and Drug Administration (Trial) YBH
Approval number: National Medicine Standard H20050667
Company Name: Chongqing Yaoyou Pharmaceutical Co., Ltd.
